Welcome to the captivating world of Pharmacology 2 in your 5th semester! Get ready to delve deeper into the realm of drugs and their effects on the human body. This semester’s study of 5th semester Pharmacology 2 will take you on a journey through mechanisms of action, therapeutic applications, and the fascinating interplay between pharmaceutical compounds and biological systems. Let’s embark on this enlightening journey together!”
Unit-1
1. Pharmacology of drugs acting on the cardiovascular system
- Introduction to hemodynamic and electrophysiology
- Drugs used in congestive heart failure
- Anti-hypertensive drugs.
- Anti-anginal drugs.
- Anti-arrhythmic drugs.
- Anti-hyperlipidemic
Unit-2
1. Pharmacology of drugs acting on cardio vascular system
- Drug used in the therapy of shock.
- Hematinics, coagulants and anticoagulants.
- Fibrinolytics and anti-platelet drugs
- Plasma volume expanders
2. Pharmacology of drugs acting on urinary system
- Diuretics
- Anti-diuretics.
Unit-3
Autocoids and related drugs
- Introduction to autacoids and classification
- Histamine, 5-HT and their antagonists.
- Prostaglandins, Thromboxanes and Leukotrienes.
- Angiotensin, Bradykinin and Substance P. e. Non-steroidal anti-inflammatory agents
- Anti-gout drugs
- Antirheumatic drugs
Unit-4
Pharmacology of drugs acting on endocrine system
- Basic concepts in endocrine pharmacology. b. Anterior Pituitary hormones- analogues and their inhibitors.
- Thyroid hormones- analogues and their inhibitors.
- Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin-D.
- Insulin, Oral Hypoglycemic agents and glucagon.
- ACTH and corticosteroids.
Unit-5
Pharmacology of drugs acting on endocrine system
- Androgens and Anabolic steroids.
- Estrogens, progesterone and oral contraceptives.
- Drugs acting on the uterus.
Bioassay
- Principles and applications of bioassay.
- Types of bioassay
- Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis, histamine and 5-HT
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